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Is Soy Safe & Effective For Menopausal Women? Here’s What The Science Says

soy for menopause

Soy — also known as soybean or soya bean — is a type of legume native to East Asia that most people recognize in the form of edamame, tofu, tempeh, tamari, miso, soy nuts, and soy milk/cheese. Its nutritional claim to fame is, for the most part, in the protein department. With all nine essential amino acids, soy is what’s known as a “complete protein” with 100 grams of cooked green soybeans containing 12.25 grams of protein.

When it comes to the effectiveness of soy for relieving menopause symptoms, there’s been a whole lot of conflicting studies…and confusion.

Case in point: certain randomized controlled trials have shown that soy IS effective for menopause symptom relief. The reason? It’s a phytoestrogen, aka a plant-based compound that, at the molecular level, is similar to that of estrogen. It mimics the role of this key hormone in the body, thus helping with hormonal fluctuations.

However, other scientific literature states that although soy is made of isoflavone compounds (genistein and daidzein) — which are a type of plant-based estrogen — it is different from the estrogen found naturally in our bodies. And while this statement was made to support the claim that plant-based estrogen may not drive breast cancer growth in the same way that our own estrogen may (more on that below), it still begs the question…if estrogen from soy products is indeed different than our body’s estrogen, what does this mean for the role of soy isoflavones on other menopause symptoms like hot flashes/night sweats, heart health, and more?

Below, we’re breaking down what we know and don’t know to date about the beneficial effects of soy consumption for menopausal and postmenopausal women.

The science on soy & vasomotor symptoms (hot flashes/night sweats)

Although the causes of hot flashes aren’t yet fully understood, evidence points to hormonal fluctuations. When estrogen levels drop, the hypothalamus (which acts as our body’s thermostat) becomes more sensitive to slight changes in body temperature. Thinking it’s overheated, the hypothalamus starts working to cool the body by shunting blood away from the core to your skin, which kick-starts a chain of events causing flushing, sweating, and an internal sensation of heat despite the fact that our body temperature isn’t actually rising.

The benefits of soy foods on the quantity and severity of hot flashes have been extensively studied, with a 2021 women’s health study published by the North American Menopause Society (NAMS) finding that a plant-based, soy-rich diet reduces moderate to severe hot flashes by up to 84%, from five per day to fewer than one per day. And get this: throughout the course of the three-month study, overall hot flashes among all participants decreased by 79%.

Although the sample size of this study was too small to draw definitive claims, researchers have seen similar promising results in larger randomized, placebo-controlled clinical trials.


The science on soy & cholesterol

Women are at a higher risk for cardiovascular disease, aka heart disease, during postmenopausal years due to declining estrogen levels. And while there are a range of contributing factors (age, family history, high blood pressure, smoking, activity levels, diabetes, etc), dietary interventions have proven particularly effective, with soybeans having been shown to lower triglycerides as well as total and LDL cholesterol.

  • Triglycerides: a type of fat that circulates in the blood, which we need a little of but don’t want too much of
  • LDL (low-density lipoprotein) cholesterol: the “bad” cholesterol that raises the risk for heart disease and stroke

Does this mean that soy-based foods are a cure-all for heart health? Unfortunately, no (if only!). And it should also be noted that this study just looked at 19 of the over 2500 varieties of soybeans — and was conducted in a lab, not on humans. But it IS safe to say that soy is a heart-healthy food for everyone, whether perimenopausal or postmenopausal.

The science on soy & breast cancer

The relationship between dietary soy and the incidence or prevention of breast cancer is complicated at best. Clinicians used to tell women with breast cancer to avoid soy at all costs because it’s a phytoestrogen (meaning it mimics the role of estrogen in the body). That said, there’s been recent research which has challenged this “avoid at all costs” claim.

In a 2020 study of 300,000 Chinese women, researchers did not find a relationship between soy intake and breast cancer risk (either positive or negative), which may be because the daily soy intake wasn’t high enough. However, this same report also included a meta-analysis of other studies, which did present an inverse relationship: a higher daily soy intake was associated with a lower risk of breast cancer, although the controlled trials referenced in this analysis had small sample sizes.

Soooo…what does this mean? Well, while we can’t say for sure that soy is protective, this does add to the growing body of evidence that it’s not harmful. Moderate amounts are safe to consume and do not need to be avoided, even by those with a history of breast cancer.

The science on soy & bone health

Unlike some other menopausal symptoms, the science behind bone loss is fairly simple: estrogen protects our bones, so when estrogen levels decrease during menopause, so too does bone density. This can lead to osteopenia (an official term for low bone density) and osteoporosis (a disease caused by significant bone loss).

Because menopause is the most common cause of osteoporosis, hormone replacement therapy (HRT) — and in particular estrogen therapy — is the most common cause of prevention and treatment. That said, there’s been some buzz lately about the role that soy can play as well.

The thing is…while the science behind menopausal bone loss is fairly simple, the relationship between soy phytoestrogens and bone health isn’t.

Several studies have examined the relationship between soy foods, soy protein isolates, and isoflavone extracts on osteoporosis prevention and overall bone health. And while many findings have been positive, they haven’t been conclusive enough to warrant definitive recommendations for treatment — particularly because of the differences in study design:

  • The studies vary in length from 4 – 24 months
  • Studies utilize different “active ingredients,” including soy protein powder, soy milk, mixed isoflavones, and individual isoflavones
  • Studies utilize different dosages from 4.4 mg/day – 118 mg/day

The bottom line: there is preliminary research that soy foods are associated with improved markers of bone health, especially among Asian women. That said, more research is needed to fully understand the optimal amounts and types of soy foods that yield these beneficial effects as part of a whole foods, plant-based diet.

READ MORE: Elektra’s Full Guide To Osteoporosis

Interested in adding more soy products to your diet?

Start with 1 serving per day, which equates to:

  • 1 cup soy milk
    Perfect in smoothies, coffee, cereal, or baked goods.
  • 1/2 cup edamame or tofu
    Edamame is the perfect snack or protein-packed addition to a salad while tofu is ideal for stir-fries.

What to keep in mind:

  • We recommend choosing organic soy whenever possible, as conventionally-produced soy often comes from large farms with high pesticide and chemical use.
  • While whole soybeans may not be optimal for those of us with autoimmune conditions, soy isoflavone supplementation is still still a viable option.
  • You should, of course, not consume soy if allergic as doing so may cause inflammation.